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The Coronary Circulation – Computerized Simulation

Mechanics and Function of Organs, Tissues and Cells

 

The Coronary Circulation – Computerized Simulation

Coronary flow is uniquely driven not only by perfusion pressure, but also by the vessels’ cyclically contracting myocardial environment. Hence realistic flow simulation must be based on detailed representation of vascular anatomy, combined with the vessels mechanics and their flow control, and the manner by which myocardial contraction affects the flow. This challenge is met by application of advanced analytical tools drawn from fluid mechanics, finite strain non-linear continuum mechanics, realistic network morphometry and modern computational capability. The models developed are used to explore important research and clinical dilemmas

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Myocardium/Vessel Interaction